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COVID-associated non-vasculitic thrombotic retiform purpura of the face and extremities: A case report.

Bunch, Connor M; Zackariya, Nuha; Thomas, Anthony V; Langford, Jack H; Aboukhaled, Michael; Thomas, Samuel J; Ansari, Aida; Patel, Shivani S; Buckner, Hallie; Miller, Joseph B; Annis, Christy L; Quate-Operacz, Margaret A; Schmitz, Leslie A; Pulvirenti, Joseph J; Konopinski, Jonathan C; Kelley, Kathleen M; Hassna, Samer; Nelligan, Luke G; Walsh, Mark M.

Clin Case Rep ; 10(12): e6790, 2022 Dec.

Article in English | MEDLINE | ID: covidwho-2172753

ABSTRACT

SARS-CoV-2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID-19 illness. Aggressive anti-COVID-19 therapy with a high-dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.

Thromboelastography-Guided Management of Anticoagulated COVID-19 Patients to Prevent Hemorrhage.

Stillson, John E; Bunch, Connor M; Gillespie, Laura; Khan, Rashid; Wierman, Meredith; Pulvirenti, Joseph; Phyu, Htay; Anderson, Stephen; Al-Fadhl, Mahmoud; Thomas, Anthony V; Kwaan, Hau C; Moore, Ernest; Moore, Hunter; Walsh, Mark M.

Semin Thromb Hemost ; 47(4): 442-446, 2021 06.

Article in English | MEDLINE | ID: covidwho-1091442

Subject(s)

Anticoagulants/adverse effects , COVID-19/blood , Drug Monitoring/methods , Enoxaparin/adverse effects , Hemorrhage/prevention & control , Heparin/adverse effects , SARS-CoV-2 , Thrombelastography , Thrombophilia/drug therapy , Adult , Aged , Aged, 80 and over , Algorithms , Anticoagulants/administration & dosage , Anticoagulants/therapeutic use , Blood Coagulation Tests , Blood Proteins/analysis , COVID-19/complications , COVID-19/therapy , Clinical Protocols , Critical Care , Enoxaparin/administration & dosage , Enoxaparin/therapeutic use , Female , Hemorrhage/chemically induced , Heparin/administration & dosage , Heparin/therapeutic use , Humans , Male , Middle Aged , Point-of-Care Testing , Postoperative Complications/epidemiology , Prospective Studies , Respiration, Artificial , Risk Factors , Thrombophilia/etiology

ABSTRACT

Subject(s)

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